It originates near Futrono in the vicinities of Ranco Lake and flows then in a general southwestern direction until discharging in Bueno River.

[1] The city of La Unión and the locality of Daglipulli are located on its western (or right) bank.

[2][3] Llollelhue River also passes near the village of El Llolly and the locality of Puerto Los Llolles.

[4] The river and these two places share an etymology derived from the local word "llolle" meaning fish trap.

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