It lies between the eastern slopes of the Cordillera Domeyko and the international border with Argentina.

The park also is characterized by extensive semi-desert plains interspersed by Quebradas.

A part of the Inca road system is found in Río Frío area.

[2] To access this area, the travel must be programmed and have official permission from the CONAF (National Forest Guard of Chile) in Antofagasta City.

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