"Lo Mejor de Tu Vida" is also recognized as one of Iglesias's signature songs and has been covered by several singers, including Tamara, Simone, Ray Conniff, Bertín Osborne and Alexandre Pires.

[1] A few years before, Iglesias was watching another performer during a music festival and thought that the song he was singing was beautiful, began asking who was the writer of the track, and someone told him that the songwriter was Manuel Alejandro.

"[2] Alejandro and Iglesias worked together again on Un hombre solo which was awarded the Grammy for Best Latin Pop Performance and sold three million copies worldwide.

[10] "Lo Mejor de Tu Vida" has been recorded by several performers, including Alexandre Pires who released it as a single from his album A un Idolo (2007), peaking at number 23 in the Hot Latin Tracks.

[14] A Cantopop version of "Lo Mejor de Tu Vida" was recorded by Hong Kong songstress, Aling Choi, in 1990, in her solo-album The Simple Life.