Loaded Pistols is a 1948 American Western film directed by John English and starring Gene Autry, Barbara Britton, and Chill Wills.

Written by Dwight Cummins and Dorothy Yost, the film is about a cowboy who protects a young man wrongly accused of murder, while trying to find the real badguys.

Larry's sister Mary (Barbara Britton) defends her brother, claiming they both loved Ed, who acted as their guardian after the death of their father.

To allude a posse, Gene takes Larry to a cabin belonging to his prospector friend, Jim Hedge (Clem Bevans).

He sets a trap for the killers and exposes Don Mason and his cohorts, Bill Otis and Dave Randall, who murdered Ed Norton in order to obtain the rich lode of iron ore on his ranch.