The main building, named Lockport High School (LHS), houses grades 9 through 12.

Lockport High School has been going through a remodeling state through the years of 2009-2012, it now has a brand-new modern style.

The building sits on a corner plot of land on Lincoln Avenue and Locust Street.

Lockport High School offers more than 150 different courses in English, Social Studies, Mathematics, Science, Languages Other Than English, Art, Music, Family & Consumer Science, Health, Business, Technology, and Physical Education.

Though the curriculum is developed and sanctioned by the New York State Department of Education, and classes are developed to prepare students to achieve success on the required Regents Examinations, most core courses offer one or two components that explore more advanced topics.

The rank in class is established by placing students in descending order from highest to lowest according to their weighted grade point average.

The school has won state titles in multiple individual and team sports including boys and girls cross country, golf, tennis, soccer, swimming, track, wrestling, and football.