Lockup is a prison documentary series, produced by 44 Blue Productions, which airs on MSNBC.

The various Lockup series explore jail and prison facilities throughout the United States, profiling notable inmates, incidents, and prison operations.

Titles within the franchise deal in specific areas as follows: Most episodes end with a 'recap', explaining what happened to a given inmate (or, on occasion, a staff member) months or years after the taping; subsequent episodes will frequently return to a given prison (and/or a given inmate) to revisit them several months later.

The cancellation of Lockup was announced on June 29, 2016, with the twenty-fifth season as the series' last.

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