List of General Hospital characters introduced in the 2000s

After leaving Rafe with a silver arrow to defend himself from harm, Alison makes her way to the Police Department, looking for information on Lucy Coe.

Janet Di Lauro of Soap Opera Digest wrote of the couple, " The minute actors Brian Gaskill and Erin Hershey Presley crossed paths on screen, the show's scribes knew they'd struck gold.

[19] Soap Opera Weekly's Joe Diliberto also praised Hershey for her work during "the crumbling of Alison's relationship with Jamal" and the beginning of her romance with Rafe.

[20] Diliberto said, "As Port Charles Alison, Erin Hershey mixed heaping amounts of amiability with dollops of sadness and a dash of bittersweet to come up with a performance sweeter than any candy.

Sonny's lieutenant and best friend, Jason Morgan, realizes that Kristina might be lying and convinces Detectives Dante Falconeri and Lucky Spencer to investigate further.

After learning that someone in Port Charles has been messing with the supply of counterfeit prescription drugs, Nadine, Nikolas, Lucky Spencer, and Sam McCall begin to investigate.

One bursts during surgery, causing the entire OR team to collapse, and the toxin to spread through the ventilating system into the board room of the hospital, where the fundraiser was being held.

Dante and Ronnie work together to find evidence Sonny Corinthos killed his wife Claudia Zacchara by testing ashes from the fireplace at his house.

Andrea Floyd debuted on June 17, 2009, in Patrick Drake's office to talk about the malpractice suit against him and his brother Matt Hunter due to the death of Brianna Hughes during surgery.

Instead, she is met by Andrea, they get into another heated argument, and Alexis drives off in a highly emotional state in the same direction where Claudia Zacchara's car accident occurs.

Andrea eventually realizes that Robin suspects her of the murder, and attempts to cover up her tracks by eliminating the one person who remembers seeing her in the hotel at the time of Brianna's accident: Edward Quartermaine.

On June 10, 2009 Patrick Drake, Robin Scorpio-Drake, and Olivia Falconeri walked into a room at the Metro Court Hotel to find Brianna Hughes, lying unconscious on the bed with Garrett.

Later that day, in an ironic twist, Edward suffered a heart attack due to the poisoning, which caused him to lose control of his car and run down Andrea down at a carnival.

[32] In 2010, Max works as the primary bodyguard for Sonny's ex-wife Brenda Corinthos and her son Alec Scott before they leave Port Charles and returned to Rome.

He used several dirty tricks to get Johnny the death penalty including fraud by forging papers stating his son was working undercover for the police and calling an unstable Lulu to the stand.

It was first announced in May, 2008, that Jason Cook, known for his seven-year portrayal of Shawn-Douglas Brady on Days of Our Lives, would appear on General Hospital in early June.

[40] Cook said of his decision to leave the series, "I was going to have to take several months off the show for all these other things I'm working on, so I am stepping away for the time being, [t]here is no talk about me coming back.

At the Floating Rib, Matt says his goodbyes to Mac, Felicia, and an emotional Maxie, who he intends to annul his marriage to, before heading off to begin serving his sentence.

Epiphany tried to give Patrick and Sabrina Santiago her support as they watched their son, Gabriel, die, knowing there wasn't any way to save the baby.

In September 2016, Epiphany suffered a devastating loss when her dear friend Sabrina Santiago fell victim to a serial killer who was roaming the hospital.

[48] In November 2005, Molly was introduced in the Glencoe tunnel with the help of Robin Scorpio, after many of Port Charles' best-known residents were involved in a train crash.

She soon begins to deal with the fallout of her family's problems, including the scandal of Alexis' affair with Mayor Floyd, and Kristina's abuse at the hands of her boyfriend, Kiefer Bauer.

[49] The character of Trevor Lansing is first mentioned in 2003 by his son, Ric who has come to Port Charles to ruin the life of his maternal half-brother, Sonny Corinthos.

Reese Marshall (formerly Tucker, born Charlotte "Carly" Roberts) is a fictional character from the ABC daytime soap opera General Hospital.

Federal prosecutor John Durant thought working to find Kristina would be the perfect opportunity for Reese to gather information on Sonny, which he could use to finally prosecute the mobster.

Jason's computer genius friend, Damian Spinelli, discovered Diane had a second hidden career as a writer, and got her help to write a book about his alter ego, Jackal P.I., and his adventures.

As their relationship progresses from purely physical, she accompanies him to a black and white ball thrown by Nikolas Cassadine in honor of his engagement to Emily Quartermaine.

Alexis finds out Rebecca is Emily's twin sister, and was sold at birth by their parents, Hank and Paige Bowen, then illegally adopted by the Shaw family.

[76] Previously Weitz was known for his Emmy award-winning role as Detective Mick Belker on hit NBC crime drama, Hill Street Blues.

"For the last several weeks, the characters on General Hospital have been talking nonstop about Anthony Zacchara, a mobster so scary his mere name makes Port Charles crime boss Sonny Corinthos (played by Maurice Benard) shiver like a Chihuahua."

Jamie Ray Newman got her start on General Hospital .
Annie Wersching portrayed Amelia in 2007.
Kari Wührer portrayed Reese in 2005.
Hennesy in 2010
Weitz originated the role in 2007.