It was an attempt to answer the requirements for the Navy's programme Hydravion éclaireur de combat ("Combat reconnaissance seaplane") for a large floatplane capable of acting as a torpedo bomber or reconnaissance aircraft.

Design of the Loire-Nieuport 10 started in 1937, with the resultant aircraft being a twin-engined monoplane of all-metal stressed-skin construction with inverted gull (or W-shaped) wings.

The deep fuselage accommodated a crew of six, with pilot and co-pilot seated in tandem, while a glazed nose was provided for the bomb-aimer/navigator.

Defensive armament was a machine gun in the nose, with another firing through a ventral hatch, and a 20 mm cannon in a dorsal turret, while it could carry two torpedoes or 1,200 kg (2,700 lb) of bombs in an internal bomb-bay.

[1] However, on 10 December 1939, the programme was cancelled as the French Navy had decided to use land based aircraft instead, with no production following of either the LN.10 or its competitors.