[citation needed] In 1915, Wilson moved to California after winning a beauty contest put on by Universal Studios and the Birmingham News.

Weber then took her to Los Angeles, where she was groomed for stardom and began playing leads opposite actors such as J. Warren Kerrigan and Frank Keenan.

Her most recognized screen portrayals are Molly Wingate in The Covered Wagon (1923), in which she was well reviewed,[8] and Daisy Buchanan in the silent film version of The Great Gatsby (1926).

Lois ventured to Broadway and television following her final role in The Girl from Jones Beach (1949) with Ronald Reagan.

[13] In 1934, her performance in No Greater Glory inspired a Birmingham, Alabama sculptor to create a monument for the city's celebration of World Peace Day.

Lois Wilson died of pneumonia at the Riverside Hospital for Skilled Care in Reno, Nevada at age 93.