"Lola's Theme" is the debut single of British house duo the Shapeshifters, featuring soul singer Cookie on vocals.

[3] "Lola's Theme" features a sample from the introduction of Johnnie Taylor's R&B hit of 1982, "What About My Love", and it was originally released at the end of 2003 on their own Nocturnal Groove label as a mostly instrumental track featuring a vocal sample taken from Anthony White's 1994 song "Love Me Tonight".

"[2] Due to its immense popularity, "Lola's Theme" was licensed from Nocturnal Groove to Positiva Records.

It is addressed to an unnamed other, presumably a love interest, who helped the singer to develop a more positive outlook on life.

In July 2024, British rapper ArrDee collaborated with the Shapeshifters, sampling "Lola's Theme" for his single "Different".