[10][11] Robert McKimson designed the prototype version of the character with Phil DeLara redesigning Honey and using her as a semi-regular in the Looney Tunes Gold Key Comics in the 1960s.

A female rabbit resembling this design appears at the end of the 1979 television special Bugs Bunny's Thanksgiving Diet albeit with the ears standing up.

Later merchandise using the character depicted her as more closely resembling Bugs, with grey fur but a more visibly feminine model and clothing, which was used until the early 1990s.

[1][14] This later design, named Lola Rabbit, was rejected as McDonald's, who had signed a contract with Warner Bros. to sell Space Jam-themed Happy Meal toys, felt that she looked too young to be paired up with Bugs romantically.

She is shown with tan fur, blonde bangs, and wears a cropped white tank top, purple/blue shorts and a matching rubber band on both ears like a ponytail.

[22] As animation director Tony Cervone explained, Lola was originally intended to be more of a "tomboy", but the production team feared that she would appear "too masculine" and chose to emphasize her "feminine attributes" instead.

As opposed to her personality in Space Jam, she is portrayed as an eccentric, scatterbrained, endearing, and cheerful young rabbit who tends to obsess over Bugs, whom she refers to as "Bun-Bun".

Lola returned in Space Jam: A New Legacy with an updated character redesign, voiced by Zendaya[5] although Soucie was initially announced to be reprising the role.

This version gained the most positive reception for her personality and her defying gender stereotypes by working hard on projects with her friends and acting as a true leader for a construction team.

She is seen with Babs Bunny and the other tiny toons together onscreen for the first time; her occupation within Acme Looniversity is implied to be sports coach, including other roles such as the head chef.

For her portrayal, Wiig received several nominations including a Primetime Emmy and won the People's Choice Voice Acting Award in 2011.

[49] Chuck Jones stated in an interview that he did not like Lola Bunny, calling her "a totally worthless character with no future and no personality" (in fact, her personality in Space Jam was not much developed, due to lack of time and her being written late into the story very quickly) and considering her "a nightmare of furvert fetishist "His opinion was shared by Maurice Noble, who created visual backgrounds for many animated shorts directed by Jones.

"[53] In 2019, after watching the original Space Jam for the first time, Malcolm D. Lee, the director for Space Jam: A New Legacy, said that he "felt off-guard on how Lola was too sexualized" and decided to turn her into the typical "strong woman" character of modern films, stating: "The original Lola Bunny was not politically correct...It's important to reflect the authenticity of strong, capable female characters."

[20] However, Lola Bunny is not the only character to see a rise in contemporary popularity, as original Looney Tunes merchandise in general has gained nostalgic value.

Kristen Wiig, who portrayed Lola Bunny in The Looney Tunes Show, received several nominations for her work and won the 1 Behind the Voice Actors Award.