However, a familial relationship between the imperial members of the gens Egnatii and Egnatius Lucillianus has been described as "extremely doubtful".
[1] But his and his sister nomina Egnatius / Egnatia and their cognomina Lollianus / Lolliana point to a direct descent connection to their given great-great-grandfather.
A pagan,[2] he was governor of Campania from 328 to 335, comes Orientis from 330 to 336, proconsul of Africa from 334 to 337, praefectus urbi of Rome in 342, consul in 355 and praetorian prefect of Illyricum for Constantius II between 355 and 356.
He encouraged the senatorial writer Julius Firmicus Maternus to write an astrological essay, the Matheseos libri VIII, that the author dedicated to Lollianus.
He married Cornelia Severa, possibly a great-great-granddaughter of Gnaeus Cornelius Paternus, by whom he had a son, Quintus Flavius Egnatius Placidus Severus.