[1] When this division began in 1987 it was known as London 2 North, changing to its final name ahead of the 2009–10 season.

The first placed team in the league won promotion to London & South East Premier while the league runner-up played the second placed team from London 1 South in a play-off for promotion.

Amersham & Chiltern, Belsize Park and Old Haberdashers were placed into Regional 2 Thames, while Brentwood, Chingford, Eton Manor, Norwich, Southend Saxons and Thurrock were placed into Regional 2 Anglia.

The top four teams in 2021–22, Colchester, Harpenden, Shelford and Sudbury, were promoted to the level five league Regional 1 South East.

Amersham & Chiltern, the champions, are promoted to National League 3 London & SE for next season.

The cancellation of National 5 South at the end of the 1995–96 season meant that London 2 North reverted to being a tier 6 league.