[7] Hughes won the 2009 Funny Women Award at the Comedy Store (London),[5] against competition from Eve Webster and Jo Selby.

Hughes had her first feature film role in comedy It's a Lot, written and directed by Femi Oyeniran, released nationwide in 2013.

London improvised a lot of the comedy material for her scenes and choreographed the numerous dance routines used throughout the film.

[6] Hughes made her BBC Radio 4 debut in August 2013 by writing and starring in her own sitcom pilot named 28 Dates Later.

Hughes launched her own YouTube comedy series No Filter in 2016, written by and starring herself based on her real-life experiences in friendship and dating.

[16][17][18] Hughes is scheduled to star in an upcoming Perfect Strangers reboot for HBO Max alongside Robin Thede.