[1] It is famous for its larval form, rather than the adult moth, primarily because of the caterpillar's defense mechanism, urticating bristles that inject a potentially deadly venom.
[4] Caterpillars of many species can cause irritation by their hollow body hairs that envenom or detach easily, or can be poisonous if ingested.
Lonomia obliqua is found in the south of Brazil in the states of Rio Grande do Sul, Santa Catarina, and Paraná.
Hematoma and gangrene-like symptoms manifested, spreading throughout the body, eventually causing massive blood leakage into the brain and, in several cases, death.
At first the cause could not be determined, although each victim stated they had "just handled a bunch of leafy branches to break the trail or gather vegetation."
Its hair growth covers its body, and each clump of spines is able to easily puncture the skin and release toxins into the victim.
[6] Lonomia obliqua has a toxic venom which causes disseminated intravascular coagulation and a consumptive coagulopathy, which can lead to a hemorrhagic syndrome.
"First described by Arocha-Pinango and Layrisse in Venezuela in 1967, the hemorrhagic diathesis caused in humans by touching the Lonomia species begins with inflammatory changes at the site of envenoming, followed by systemic symptoms such as headache, fever, vomiting, and malaise.
After 24 hours, a severe bleeding disorder ensues, leading to ecchymosis, hematuria, pulmonary, and intracranial hemorrhages, and acute kidney injury.
It effectively reverses the coagulation disorders induced by Lonomia obliqua venom, and patients treated with this antiserum recover rapidly.
In particular the component called "Lopap" (L. obliqua prothrombin activator protease) has exhibited anticoagulant and anti-apoptotic qualities.