Lophius beroe was first formally described in 1981 by the American ichthyologist John H. Caruso with its type locality given as "Western North Atlantic, 24°24'N, 80°00'W, depth 730-860 meters".

[2] The genus Lophiodes is one of 4 extant genera in the family Lophiidae which the 5th edition of Fishes of the World classifies in the monotypic suborder Lophioidei with the order Lophiiformes.

The specific name, beroe, is the name of a sea nymph from Greek mythology, the daughter of Oceanus and Tethys.

The first spine on the head is the angling pole, the illicium, has a flap of flesh, the esca, with a cirrus at its tip and more cirri at its base, this is used as a lure to attract prey to within reach of the large mouth.

[1] This species is found at depths between 347 and 860 m (1,138 and 2,822 ft), typically in deep coral reefs and the rubble of Lophelia pertusa.