The rusty-bellied brush-furred rat (Lophuromys sikapusi) is a species of rodent in the family Muridae.

The range of L. sikapusi species extends from Sierra Leone to the Ivory Coast, Uganda, North Angola, Tanzania, Benin, West Kenya, and Zaire.

[3] They possess a short tail length in comparison to most African rodentia species.

L.sikapusi possesses an approximately similar head to tail body length ratio in comparison with other African rodents.

[5] Their cheek teeth have three rows of cusps, not only two as seen in Cricetidae (the family consisting of voles, lemmings, and New world rats).

[3] The diet of L. sikapusi is characterized by insects such as ants, reptiles, seeds, palms, fibre, soft-bodied invertebrates, and vegetable materials that are abundant in the tropical land environments.

[8] It is thought to aid the young to absorb large amount of milk in their stomach during period of growth.

Their stomach also maintains a relatively high pH range so the enzyme salivary amylase may continue to digest carbohydrates, starch, and glycogen from the food consumed.

[1] This type of brush-furred mice produces small litters of offspring, called pups, after a gestation period of approximately 21 days.

[7] The infant rusty-bellied brush-furred mice become active in four to seven days, and their eyes begin to open.