Lorenzo is a city in Crosby County, Texas, United States.

According to the United States Census Bureau, Lorenzo has a total area of 0.97 square miles (2.5 km2), all land.

[5] The local economy is supported by agriculture, with cotton being the most important crop.

Wheat, soybeans, milo, and various other crops are also produced in the Lorenzo area.

As of the 2020 United States census, there were 964 people, 346 households, and 254 families residing in the city.