Lorenzo Antonetti (31 July 1922 – 10 April 2013) was a Cardinal in the Catholic Church, who held several positions in the Vatican diplomatic service.

[citation needed] Antonetti was born on 31 July 1922 in Romagnano Sesia, Kingdom of Italy.

He joined the Vatican Secretariat of State in 1951 and served as an attaché and later secretary in nunciature in Lebanon from 1952 to 1955.

In 1995 Pope John Paul II gave him the position of Pro-President of Administration of the Patrimony of the Apostolic See, Roman Curia, losing the "pro-" upon elevation to cardinal.

[citation needed] Pope John Paul II created him Cardinal-Deacon of Saint Agnes in Agone on 21 February 1998.