He has appeared in more than thirty European films and television series since then, including Le héros de la famille, The Stone Council (both opposite Catherine Deneuve), André Téchiné's The Witnesses, Krzysztof Zanussi's Black Sun, Carlos Saura's I, Don Giovanni and the highly acclaimed Italian TV series Le cose che restano.

In 2009 he received the Susan Batson Award for his performance in Due vite per caso at the San Francisco's NICE Film Festival.

He also appeared in the American independent comedy In search of Fellini (opposite Maria Bello), the acclaimed short film Snowflake (as Tracy Middendorf's love interest and for which he also served as an executive producer) and guest starred in the TV drama Medici: Masters of Florence.

On stage, Balducci has starred in several productions of Dignità Autonome di Prostituzione in both Italy and Spain and, in 2017, he was part of the ensemble cast of Luciano Melchionna's Spoglia-Toy.

After the debut at Teatro dei Filodrammatici in Milan, the show run successfully at the Off-Off Theatre in Rome and then continued to tour around Italy.