Lorenzo Bernucci (born 15 September 1979 in Sarzana) is an Italian former professional road bicycle racer.

He rose to international prominence when he won stage 6 of the 2005 Tour de France, when riding for Fassa Bortolo.

Upon Fassa's demise at the end of 2005, Bernucci secured a contract with T-Mobile.

Bernucci was fired from T-Mobile in September 2007 after testing positive for Sibutramine.

T-Mobile judged he had broken the internal code of conduct so fire him immediately.