[2] The newspaper covers news, politics, opinion, arts and entertainment in the Los Angeles area, and includes some national and international coverage from the Washington Blade.

Following his departure from The Pride LA in 2017,[5] publisher Troy Masters launched the Los Angeles Blade a biweekly newspaper to serve "the second largest market in the country, and one that was underserved by alternative media.

[9] During the 2022 mpox outbreak in California, the Los Angeles Blade hosted two town hall meetings — one in West Hollywood and another in Monterey Park — to alert residents to the emerging threat.

[14] Following publisher Troy Masters' sudden death on December 11, 2024, the newspaper's management team announced that the organization would continue under the leadership of local editor Gisselle Palomera.

The Blade is distributed throughout Southern California, with a focus on areas with significant LGBT+ populations, such as West Hollywood, Silver Lake, and Los Feliz, and as far as Palm Springs.