Founded in 2010 as the Los Angeles Blues, the team currently plays in the Western Conference of the USL Championship, the second tier of the American soccer system.

[7] In January 2012, the Blues announced the hiring of Steve Donner (formerly CEO of Orlando City) as vice president of business operations to focus on improving marketing for the club and to bring professionalism to the front-office.

[13] OCSC went on to finish second in the Pacific Division, and advance to the USL Championship Final, defeating Tampa Bay Rowdies away at St. Petersburg, Florida, 3–1 in regulation.

[17] Karlsen led the team to a season-end 2nd place Western Conference placement at 17-11-6, earning two consecutive USL Championship Coach of the Month awards for July and August.

[19] Orange County lost star forward Milan Iloski during the 2024 January transfer window to Danish Superliga club FC Nordsjælland.

[26] Under Danny Stone, Orange County was able to rescue their season and clinch a visit to the playoffs, where they were eliminated in the Western conference semi-finals against the Colorado Springs Switchbacks FC.

[27] In October 2023, it was announced the City of Irvine and Orange County SC had drafted a 5-year agreement for the team to operate Championship Soccer Stadium.

[30] The clubs were in a dispute over who would play at Championship Soccer Stadium in late 2022, after leaked documents showed the Galaxy organization attempted to seize full-time usage of the venue.

[31] The rivalry has slowed down as of late, as after LA Galaxy II moved to MLS Next, the third tier of the American soccer system, both teams have only met in pre-season friendlies.