Los Homerun-es is a compilation album and fifth overall of Reggaeton recording artist Daddy Yankee.

Even though it was an independent album, it featured other huge reggaeton artists, like Nicky Jam, Don Omar, Julio Voltio.

To promote the album, he toured for the first time in Panama, Nicaragua and Honduras.

The lead single "Seguroski" become his first song to chart and gain moderate airplay in the United States.

Following the success of the album, he also performed on the first reggeaton summer fest at the Madison Square Garden in New York and his first major show as a headliner artist at the Roberto Clemente Coliseum in San Juan, Puerto Rico in August 2003.