In June of that year, the group appeared in an episode of CMT's "Crossroads" show with country music legend Ronnie Milsap.

On October 23, 2008, Los Lonely Boys sang the national anthem to open game two of the 2008 World Series in St. Petersburg, Florida.

The trio released a tribute EP titled "1969" on October 13, 2009, paying homage to the 40th anniversary of the titular year with covers of Santana's "Evil Ways", The Doors' "Roadhouse Blues", Blind Faith's version of Buddy Holly's "Well All Right", The Beatles' "She Came in Through the Bathroom Window", and Tony Joe White's "Polk Salad Annie".

Rockpango, which features 11 original tracks, marks the first full-length studio album released by the band on their LonelyTone imprint for Playing in Traffic Records.

The album represents new territory for the Boys, with the conjunto touches on "Blame It On Love" and the reggae groove of "Give a Little More", among many other new sonic elements.

In 2016, the band recorded a cover version of John Fogerty's "Born on the Bayou", to be included in the project Quiero Creedence.

[7] In October 2019, Los Lonely Boys canceled all upcoming performances after Jojo Garza announced he was leaving the group, causing the band to take a temporary hiatus.

[8] On April 21, 2022, with Jojo having allegedly changed his mind after two years, Los Lonely Boys announced they were joining The Who on some tour dates in Dallas, Houston, and Oklahoma City.