Lost Creek is a town in Harrison County, West Virginia, United States.

[5][6] The creek itself was named after messages carved on nearby trees during early European exploration of the area.

[7] The Daniel Bassel House and Lost Creek Baltimore and Ohio Railroad Depot are listed on the National Register of Historic Places.

[8] Lost Creek is located at 39°9′30″N 80°20′53″W / 39.15833°N 80.34806°W / 39.15833; -80.34806 (39.158451, -80.348165) in southern Harrison County.

[9] According to the United States Census Bureau, the town has a total area of 0.97 square miles (2.51 km2), all of it land.

18.9% of all households were made up of individuals, and 8.1% had someone living alone who was 65 years of age or older.

24.5% of all households were made up of individuals, and 13.6% had someone living alone who was 65 years of age or older.

In 2021, a new Lost Creek Elementary School was constructed adjacent to the South Harrison campus.