Lou Blackburn (November 12, 1922 – 7 June 1990) was an American jazz trombonist.
During the 1950s, he played swing music with Lionel Hampton, and also Charlie Ventura.
In the early 1960s, he began performing with musicians like Cat Anderson, among others.
From 1970, he lived in Germany, where he toured successfully with his ethno jazz band Mombasa.
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