Louie has historically been regarded as a less common variant of the given name Louis.
It originated in the United Kingdom (where Louis is pronounced /ˈluːi/) as a more regularly-spelled version without a silent ⟨s⟩.
[1] However in both 2022 and 2023 UK baby names popularity it has ranked above Louis.
[2] In the United States, Louis (there pronounced /ˈluːɪs/) is far more common.
The name is unisex; it is usually considered a masculine given name, as a derivation of Louis, but is occasionally given to girls as a diminutive of Louise.