He then spent two years in Paris, where he studied at the École des Beaux-Arts and took a position in the studios of Jean-Baptiste Regnault, who encouraged him to compete in the Prix de Rome.
Illness from overwork prevented him from doing so, however, and he found it necessary to seek treatment at home twice during those years.
Upon returning to Geneva, he set up as a portrait painter and gained a considerable reputation as such, but decided that he preferred to paint genre scenes.
He also took students, including Fritz Zuber-Buhler and François Bocion, and was his son's first teacher.
He had many admirers in Prussia, including King Frederick William III, and he was named an honorary member of the Prussian Academy of Arts in 1826.