He pioneered Eastern Christian and Assyrian Chaldean literary research and made major contributions to the publication of manuscript texts.

He adopted at that time the name of 'Louis' out of devotion for the young Jesuit saint Louis Gonzaga.

In 1878, he returned to Lebanon and taught Arabic Literature at the Jesuit Saint Joseph College in Beirut for 10 years.

Finally in 1894, he settled in Beirut, Lebanon, where he continued his academic career at Université Saint-Joseph.

Famous Turkish poet Mehmet Akif Ersoy said that his work "Majani al-Adab" can be used in teaching Arabic.