After attending Rosenburg Academy and the colleges of Lissa, Nikolsburg, and Presburg, he matriculated at the University of Berlin, where he took the degree of Ph.D.[1] On a visit to Hamburg he was given the task of arranging the Oriental coins in the Sprewitz collection.
Coming to London, he obtained introductions to the Duke of Sussex and Admiral Sir Sidney Smith, through whom he became known to scholars and patrons of learning in England.
In 1836 he undertook, under the auspices of the Duke of Sussex and Sir Sidney Smith, a three years' tour in the Middle East, to extend his knowledge of its languages.
[1] In 1839 Loewe went to study in the Vatican Library, and Sir Moses Montefiore passed through Rome on his second journey to the Palestine.
He became examiner for oriental languages to the Royal College of Preceptors in 1858, and in the same year opened a Jewish boarding-school at Brighton.
When in 1868 Montefiore founded the Judith Theological College at Ramsgate, he chose Loewe as principal and director, and he was in that post for twenty years.
In 1841 Loewe prepared an English translation of Efés Dammîm, a series of conversations at Jerusalem between a patriarch of the Greek Orthodox Church and a chief rabbi, written in Hebrew by Isaac Baer Levinsohn in 1839, on the occasion of a blood libel in Soslow, Poland.