Part of the faction who opposed Cardinal Richelieu and his policy of war with Spain, he was killed leading a revolt at the Battle of La Marfée in 1641.

In 1636, Louis conspired with his cousin Gaston d'Orléans and the count of Montrésor with the intention to murder Cardinal Richelieu and depose the King, but the plot failed.

This was due to the late slow arrival of the King's forces through muddy roads and the surprise cavalry attack from their flank from behind a hill.

[3] He was buried in the Soissons family tomb at the Chartreuse de Bourbon-lez-Gaillon in Gaillon, in the French province of Normandy.

The county of Soissons was passed onto his only surviving sister Marie de Bourbon, Princess of Carignano and wife of Thomas Francis of Savoy, a famous general.