Louis de Bourbon-Vendôme (2 January 1493, in Ham, Picardy, France – 13 March 1557), was the son of Francis, Count of Vendôme and Marie of Luxembourg and a French prince du sang and religious leader.
Elected Bishop of Laon on 24 April 1510 with an exemption because he had not reached the canonical age, he took his vows in front of King Francis I 9 June 1517 and was elevated to cardinal in the consistory of 1 July 1517 ; he was appointed as the first abbot of St. Denis in 1529, Archbishop of Sens in 1535, Father, Lord of Conde.
He was present at the coronation of Queen Claude of France in the abbey of Saint-Denis (10 May 1517), signed the marriage contract of Dauphin Francis with Mary of England.
He baptized Prince Francis (Fontainebleau, 2 February 1542) and Henry of Navarre (1554), celebrated the marriage of Madeleine of France (1520–1537) with James V of Scotland (Notre-Dame de Paris, 1 January 1536).
He took part in the war council of 18 February 1536 decided that the resumption of hostilities with Emperor Charles V. He presided over the convocation at Melun in 1548.