Although her career began when she was a child, it was for "the pathos and dignity of her elderly, motherly roles"[1] that she was best known.

She made her stage debut at the age of four at the Queen's Theatre, Manchester as Henri, the child in Belphegor.

In 1914–15 she toured Britain in The Blindness of Virtue, The Second Mrs. Tanqueray (in the title role) and Outcast.

[4] After her success in Ruts at the Court, Hampton began a long series of London parts.

[6] The Times commented that she would be remembered particularly for her performance as "the weary, kindly, heartbroken woman who runs a shop" in Nine Till Six, in the title role of Čapek's The Mother, and for "her exquisite portrait … of a woman whose upbringing and memories enable her to meet death with smiling dignity" in For Services Rendered.