Louisiana's 38th State Senate district is one of 39 districts in the Louisiana State Senate.

It has been represented by Republican Barry Milligan since 2020, following Milligan's 2019 defeat of Democratic incumbent John Milkovich.

[3] District 38 covers all of DeSoto Parish and southern parts of Caddo Parish in Ark-La-Tex, including the towns of Greenwood, Keithville, Stonewall, and Mansfield, as well as a small portion of southern Shreveport.

[4] Louisiana uses a jungle primary system.

If no candidate receives 50% in the first round of voting, when all candidates appear on the same ballot regardless of party, the top-two finishers advance to a runoff election.