Louisiana is a city in Pike County, Missouri, United States.

Louisiana is located in northeast Missouri, on the Mississippi River, south of Hannibal.

The latter enters Louisiana from Illinois via the Champ Clark Bridge, named for a former US Speaker of the House from nearby Bowling Green.

[4] Other notable early residents were Samuel Caldwell and Joel Shaw, both of whom purchased land from Basye in 1818.

Louisiana proved to be a profitable shipping point on the Mississippi River, and that wealth led to numerous substantial antebellum homes.

Louisiana is one of three communities forming the 50 Miles of Art corridor, linked by history, heritage and Route 79; Louisiana, Clarksville and Hannibal are home to many artists, crafts persons and artisans.

In 1946, the town was the site of a Fischer-Tropsch plant capable of producing liquid hydrocarbon fuels.

Seven scientists brought into the United States by Operation Paperclip from Nazi Germany took part in the research.

[5] Louisiana hopes to be part of the "green energy" revolution as a former ammonia plant has been converted for the study and production of synthetic fuels.

The event is held the third weekend in October and is attended by over 8,000 people annually.

In addition to the Georgia Street Historic District, the Charles Bacon House, Capt.

George and Attella Barnard House, Bethel Chapel AME Church, City Market, Goodman-Stark House, Louisiana Chicago & Alton Railroad Depot, Louisiana Public Library, North Third Street Historic District, Pike County Hospital, and Gov.