It spans 80.9 miles (130.2 km) and runs from west to east.

LA 112 is a mostly rural two lane highway with a maximum speed limit of 55 miles per hour (89 km/h) per hour.

The western terminus is at an intersection with U.S. Route 171/U.S.

Although the highway runs west to east it meanders through three parishes and on the map appears to make a large S. Beginning at the western terminus LA 112 travels northeast and intersects with LA 113 in Sugartown, enters Allen Parish, and merges running concurrent a short distance with LA 377.

LA 112 swings east then northeast, like a large check mark, before resuming an eastern route, passing through the community of Midway, and intersecting Interstate 49, before terminating in Lecompte at an intersection with U.S. 167/ U.S. 71.