Much of the route is proposed to be turned over to local control as part of the Louisiana Department of Transportation and Development (La DOTD) road transfer program.

Just before the highway passes the local high school, the median is discontinued as the roadway narrows.

After passing Lane Regional Medical Center, the median reappears, and the highway proceeds through the less developed east side of town.

[3][4][5] Narrowing to an undivided two-lane highway, LA 64 bends to the southeast and crosses the Comite River into the city of Central, an incorporated collection of rural communities and residential subdivisions.

The highway maintains a southeastern trajectory for the next 5.2 miles (8.4 km) to a T-intersection with LA 409 (Liberty Road) at Indian Mound.

[13][14] The paving project smoothed out some sharp bends in the roadway on the east side of Zachary.

[15][16] Paving resumed eastward from Fred a decade later and was completed past Deerford by 1953[17][18] and to Indian Mound shortly after the 1955 renumbering.

[19][21] Shortly after the 1955 renumbering, the route was extended west a short distance to Samuels Road, a gravel portion of LA 68 that would become the current alignment of US 61, bypassing the Old Scenic Highway alignment once improvements were completed in 1961.

With the 1955 renumbering, the state highway department initially categorized all routes into three classes: "A" (primary), "B" (secondary), and "C" (farm-to-market).

A curve at Indian Mound was smoothed out when a new bridge was constructed on LA 37 across nearby Sandy Creek in 1957.

Around this same time, the portion of LA 64 running through Zachary was widened to four lanes, increasing the traffic capacity through this growing suburb.

[31][32] In 2015, LA 64 was shortened on its west end when 1.4 miles (2.3 km) of the route west of LA 964 was returned to local control, leaving a section of road adjacent to US 61 disconnected in terms of state maintenance.

[1] La DOTD is currently engaged in a program that aims to transfer about 5,000 miles (8,000 km) of state-owned roadways to local governments over the next several years.

[34] Louisiana Highway 64-1 (LA 64-1) runs 1.98 miles (3.19 km) in an east–west direction between US 61 and a local road west of Zachary.

From the west, LA 64-1 begins at a point on US 61 (Samuels Road) between Baton Rouge and Port Hudson.