It proceeds west along Bayou Sale Road and makes a brief dip to the south before heading in a general northerly direction for the remainder of its route.

Traveling alongside the east bank of Bayou Grand Caillou, LA 57 passes through Boudreaux and Ashland.

LA 57 is an undivided, two-lane highway from its southern terminus to an intersection with Thompson Road in Houma.

It continues as an undivided, three-lane highway with middle turning lane to East Woodlawn Ranch Road.

From there it becomes an undivided five-lane highway until it reaches the intersection of Tunnel Boulevard where the turning lane disappears.