The Louisville–Memphis rivalry is a sports rivalry between the University of Louisville Cardinals and University of Memphis Tigers.

[1] The two NCAA Division I schools compete in various sports, with men's basketball and college football in particular being prominent.

[1] Both schools were represented in a 2008 Sheraton commercial featuring fans of other college sport rivals such as Michigan/Ohio State, Duke/North Carolina, USC/UCLA, and Syracuse/Georgetown.

[2][3] The series between the men's basketball programs began in 1949.

[5][4] Louisville joined the Atlantic Coast Conference in 2014.