[1] After many months of hard work, Mavrokefalidis was almost always a member of the starting five in PAOK, creating havoc to the opposition's defense with his ability to get to the rim and make easy buckets or exciting dunks.

During the summer of 2006, Mavrokefalidis was signed by Virtus Roma of the Italian League and EuroLeague, but he was not established as a key member of the team, averaging just 2 points and 1 rebound per game.

In February 2007, he was transferred from Roma to Pamesa Valencia of the Spanish ACB League, in exchange for Roberto Chiacig and Jon Stefánsson.

[5] In 2011, Mavrokefalidis was signed by the Russian League club Spartak Saint Petersburg[6] to a 2-year contract worth €2.4 million euros net income.

[12] Mavrokefalidis was the top scorer of AEK Athens in the 2015–16 Greek Basket League season, averaging 14.5 points per game.

[15] On 20 February 2017 Mavrokefalidis returned to the Greek club AEK Athens, signing a contract with them for the rest of the season.

[19] On 8 December 2020 he returned to Ionikos, after a fallout with newly appointed Peristeri coach (and his former Panathinaikos boss), Argyris Pedoulakis.

Mavrokefalidis started the 2021-22 campaign with 2nd division club Tritonas Sepolion, bringing them to the brink of Greek Basket League promotion, before returning once again to Ionikos Nikaias and helping them avoid relegation.

In 2011, Mavrokefalidis was given a 2-month suspension from all competitions by the Hellenic Basketball Federation, for refusing to play for Greece's national team for the second consecutive summer.