"Love Is Strange" is a crossover hit by American rhythm and blues duet Mickey & Sylvia, which was released in late November 1956 by the Groove record label.

"Love Is Strange" peaked at #1 on Billboard magazine's most played by jockeys R&B Singles chart on March 6, 1957 and #11 on the Hot 100.

[9] In 2004 "Love Is Strange" was inducted into the Grammy Hall of Fame for its influence as a rock and roll single.

The song was featured in the 1987 film Dirty Dancing and included on the soundtrack, which is one of the best-selling albums of all time.

The song is "covered" by the fictional Scottish band "The Majestics" in the BBC Television series Tutti Frutti (1987), starring Emma Thompson, Robbie Coltrane, Maurice Roeves, Jake D'Arcy and Stuart McGugan.

The spoken part is referenced by Lou Reed at the end of his song "Beginning of A Great Adventure" on his 1989 album New York.

The song appears also in the Dennis Potter 1993 TV miniseries Lipstick on Your Collar where Mickey and Sylvia become the two main characters.

The song also is played in the 2000 HBO hit show The Sopranos, season two, episode 6 ("The Happy Wanderer").