The school's motto is Natus Ad Majora ("Born for Greater Things").

Loyola Public School is managed and administered by members of the Society of Jesus (Jesuits).

In presecondary and secondary education alone, in South Asia, 820 Jesuits run 447 schools with a student population of 344,000.

The foundation stone of this second Jesuit educational institution in Andhra Pradesh was laid on 30 January 1964 by the Chief Minister of the State Dr. N. Sanjeeva Reddy.

That includes mandatory classes and board exams in English language and literature, Physics, Chemistry and Biology.

Loyola Public School offers Computer Applications as the optional and a choice between Hindi and Telugu for the 2nd language.

The school has continuously given a 100% result (all students attempting the exam exceed the set limit for pass mark ie- 35%) for decades at a stretch.

The school has a progressive teaching approach using smart learning tools when required.