Glasgow is well known for his energetic DJ sets, of which manipulate mainstream sounds by craftily layering pop tracks and vocal samples between Baltimore club, ghetto house, hardcore, electro and techno.

I enjoy taking a popular narrative, whether that may be a highly recognizable artist or song, or even samples from a TV show or interview, and flipping them on their head.

He briefly went by Funky$punk in mid-2010, later adopting the LSDXOXO moniker because "it sounded like an AIM username, [...] was super troll-y, and that's just how [he] approached music as an artist".

[3] In 2010, Glasgow began self-releasing his Spit or Swallow series of mixtapes on Tumblr, which were complied of mashups of popular songs from artists such as Rihanna, Crystal Castles, M.I.A., Lady Gaga, and La Roux.

One of Glasgow's more well-known works is the song "Truth Tella" which features Cakes da Killa rapping over a chopped and screwed sample of "Lavender Town" from a Pokémon game.

[8] In May 2021, Glasgow released his highly anticipated third EP Dedicated 2 Disrespect through XL Recordings, containing four tracks that presented his own songwriting and vocals rather than music samples as his previous works had featured.