Born in Vila Velha, Espírito Santo, Luís Henrique began his professional career at Botafogo de Futebol e Regatas.
He made his debut on 3 July 2015, at the age of 17, starting in a Série B against Sampaio Corrêa at the Estádio Olímpico João Havelange, scoring two goals in the first half of a 5–0 victory which kept his team at the top of the table.
He made his Série A debut on 22 May of that year, coming on as a late substitute for Neílton in a 1–1 away draw against Sport.
[4] On 15 January 2020 it was confirmed, that Helsinki's cooperation club, Vejle Boldklub from Denmark, had signed Henrique.
In the last 16, against New Zealand at the Estadio Sausalito in Viña del Mar, he won an added-time penalty when fouled by James McGarry, and converted it for the only goal of the game.