[2][3] Mandziy was born on 10 May 1973 in the village Opaka, Ukraine [uk] located in Drohobych Raion, Lviv Oblast, Ukrainian SSR.

[4][1] In 2015, Mandziy ran for the Lviv Oblast Council in constituency number 8 for the party Petro Poroshenko Bloc.

[6] From 2016 to 2019, she headed the Department of Education and Science at the Lviv Oblast State Administration.

[7] On 25 March 2020, she was appointed the Acting Minister after the resignation of her predecessor Hanna Novosad.

[4] Mandziy's Facebook page posted a message from her family stating that she "had been battling a serious illness for the past year and a half", but no cause of death was given.