[5] On 8 September 2013, García made her senior debut for newly-promoted first division team Oviedo Moderno at the age of 15.

She appeared as a 67th-minute substitute for Irene del Río on the opening day of the 2013–14 Primera División as Oviedo lost 2–1 to Valencia.

[citation needed] Following Oviedo's relegation at the end of the 2015–16 season, García remained in the Primera División and signed for reigning champions Athletic Bilbao in June 2016[7] – under their self-imposed player restrictions, the circumstances of her birth made her eligible to play for the all-Basque club.

She made her debut on 3 September 2016, starting in the opening game of the season and scored in the 2–0 win over Fundación Albacete.

In six seasons, she scored 63 goals in 161 appearances in all competitions to help the club achieve a highest league finish of third in 2017–18, also reaching the Copa de la Reina semi-finals twice.

[11] On 25 July 2022, García signed a two-year contract with English Women's Super League club Manchester United.

[15] In February 2024, during the 2023–24 season, García scored United's only goal in a 3–1 defeat to Arsenal in front of a record-breaking WSL crowd of 60,160 at a sold out Emirates Stadium.

[23] García started all five games in the tournament and finished second in the golden boot race with five goals, one behind Stefanie Sanders of Germany.

[24] The following year she represented Spain at the 2016 UEFA Women's Under-19 Championship in Slovakia as they finished as runners-up, losing to France 2–1 in the final.

[25] She was recalled to the squad later in the year for the 2016 FIFA U-20 Women's World Cup in Papua New Guinea, playing in all four games and scoring three goals: two in a group stage victory over Canada and another in a 3–2 defeat after extra-time to North Korea in the quarter-finals.

[38] She was one of Las 15, a group of players who made themselves unavailable for international selection in September 2022 due to their dissatisfaction with head coach Jorge Vilda, and among the dozen who were not involved 11 months later as Spain won the World Cup.