Lucía Guzmán (born 1945) is an American minister and politician who served in the Colorado Senate from the 34th district as a member of the Democratic Party from 2010 to 2019.

Prior to her tenure in the state senate she served on the school board in Denver and led the Colorado Council of Churches.

Guzmán was born to farm workers from Mexico and educated at Sam Houston State University and the Iliff School of Theology.

During her tenure in the state senate she served as the Minority Leader until she resigned in protest of the Republican's handling of sexual harassment cases in the legislature.

[5][6][4] Paula Sandoval resigned from the Colorado Senate to serve on the Denver city council in 2010, and Guzmán was appointed to replace her.

[19] She resigned her position as Minority Leader in protest of the Republican's handling of sexual harassment allegations against members of the state senate.

[24][25] Guzmán was among thirty-seven legislators who endorsed a letter in 2018, calling for Planned Parenthood to allow for their workers to form a union.