[1] Cuénot spent two years working on mice and came to the conclusion that three “mnemons” (genes) are responsible for the production of one “chromogen” or pigment and two “distases” enzymes.

[6][7] The mouse and population geneticist Sewall Wright credited Cuénot with the discovery of multiple alleles and the one-gene one-enzyme hypothesis.

[10] The entry on "Albino" in the Encyclopædia Britannica (11th, 1911) does fully appreciate Cuénot's work on the relationship between determinants (genes) and ferments (enzymes):[11] Before we can inquire into the cause and meaning of albinism it will be necessary first to consider the nature Of pigmentation...

In spite of the inquiry being only in its initial stages, there is already good evidence to believe that Cuénot's theory is correct, and that an albino is an individual whose skin lacks the power to secrete either the ferment or the chromogen.

After the First World War he never returned to his studies on mice and moved on to designing a theory of evolution, halfway between en vogue French Lamarckism and Darwinism.