She is the fourth-oldest verified person ever,[1] as well as the oldest confirmed survivor of the COVID-19 pandemic, having tested positive for SARS-CoV-2 a month before her 117th birthday.

[2][3] As a young adult, Randon converted to Roman Catholicism and worked as a governess, teacher, nun, and missionary before retiring at the age of 75 in 1979.

Her living siblings included three older brothers and a twin sister named Lydie, who died a year after they were born.

[5] She later joined the Catholic order Daughters of Charity in 1944, taking the name Sister André in honour of her elder brother.

[7] Randon retired from full-time work in 1979 and entered the EHPAD in the Marches at Savoie, where she continued to care for the elderly until she was 100 years old.

[13] Randon died in her sleep from natural causes at her nursing home on 17 January 2023 at the age of 118 years and 340 days as the fourth-oldest verified person ever.